Heisman Trophy Finalist Troy Davis was tremendous, rushing for 378 yards on 41 carries for four touchdowns as Iowa State won its second straight game for the first time in 69 contests, a 45-31 decision over Missouri. Davis' rushing total was the third-highest in NCAA Division I history at the time and left him just 83 yards short of 1,000 yards after four games. TCU's LaDainian Tomlinson rushed for 406 yards against UTEP in 1999 to bump Davis' total to fourth all-time.

The Cyclones shut out Missouri, 21-0, in the fourth quarter as Davis had 16 carries for 175 yards and a pair of TDs. Thanks to a great stand by the Iowa State defense, the Cyclones out-gained the Tigers 208-76 in the final 15 minutes and controlled the football for the last 9:14 of the period.

Davis was named USA Today Player of the Week for his effort against the Tigers and was Big 12 Conference Offensive Player of the Week for the second straight time. The contest marked the first time in 20 years that the Cyclones had scored more than 40 points in consecutive games. The combined total of 87 points against UNI and Missouri was Iowa State's highest consecutive-game total in 10 years.

ISU nose guard Greg Schoon earned team defensive MVP honors, making five tacklesand causing a key Missouri fumble at the Cyclone 5-yard line. The ISU offense responded by driving 94 yards in 53 seconds for a touchdown and a 17-14 halftime lead.

Former Cyclone linebackers coach DeMontie Cross recorded 13 tackles (one unassisted, 12 assisted), along with an interception to pace the Tiger defense.